Key result
Pulmonary embolism in lung cancer is associated with adenocarcinoma histology in ~61% of cases.
Why the study?
Clinical studies on patients with lung cancer having asymptomatic pulmonary embolism were barely reported.
What are the risk factors and survival outcomes for asymptomatic pulmonary embolism in patients with lung cancer?
Population
84 patients with lung cancer including 28 with pulmonary embolism and 56 with lung cancer alone
Comparison
Lung cancer with pulmonary embolism vs lung cancer alone
Design
Retrospective clinical data review
Authors
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Small retrospective series on asymptomatic PE in lung cancer; leaves open incidence, screening, and management questions.
Case-Control (n=84)
No
What are the risk factors and survival outcomes for asymptomatic pulmonary embolism in patients with lung cancer?
p-value: p=<.01
In patients with lung cancer, asymptomatic pulmonary embolism is associated with lung adenocarcinoma, hyperleukocytosis, and elevated d-dimer, and has a longer median survival time compared to symptomatic pulmonary embolism.
Li et al. (2017) conducted a case-control in Lung cancer with or without pulmonary embolism (n=84). Pulmonary embolism vs. Lung cancer alone was evaluated on Adenocarcinoma frequency (p=<.01). Pulmonary embolism in lung cancer patients was associated with a higher frequency of adenocarcinoma (60.7%, P<0.01) compared to controls, while asymptomatic cases had a median survival of 7.2 months.
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