Why the study?
Does acebutolol compared to propranolol affect forearm blood flow in hypertensive patients?
Population
9 hypertensive patients
Comparison
Acebutolol 400 mg oral daily for 2 weeks vs Propranolol 80 mg oral daily for 2 weeks
Design
Other, open-label
Follow-up
2 weeks per treatment period
Authors
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Acebutolol may sustain BP reduction better with less forearm vasoconstriction than propranolol; hypothesis-generating in small open study.
Does acebutolol compared to propranolol affect forearm blood flow in hypertensive patients?
In hypertensive patients, cardioselective acebutolol preserves resting forearm blood flow compared to non-selective propranolol.
Ireland et al. (1981) studied this question.
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