Key result
A novel competitive binding assay quantified functional rIGFBP-3 in rat serum, showing levels increased from 1.63 mg/l in young to 3.41 mg/l in old rats (p<0.05).
The described competitive binding assay provides a novel and functional method for quantifying IGFBP-3 in rat serum.
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Novel assay enables functional IGFBP-3 quantification in rats; leaves open human translation and clinical relevance.
J. Frystyk (1998) studied this question. Competitive binding assay was evaluated on rIGFBP-3 levels. A novel competitive binding assay quantified functional rIGFBP-3 in rat serum, showing levels increased from 1.63 mg/l in young to 3.41 mg/l in old rats (p<0.05).
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