Key result
The D/D genotype of the ACE gene was associated with significantly faster marathon running speeds compared to the I/I genotype (5.46 vs 5.31 m/s, p=0.005) among Japanese elite runners.
Why the study?
Is the ACE gene I/D polymorphism associated with endurance running performance in Japanese elite runners?
Observational (n=372)
Is the ACE gene I/D polymorphism associated with endurance running performance in Japanese elite runners?
Absolute Event Rate: 5.46% vs 5.31%
p-value: p=0.005
The D allele of the ACE gene I/D polymorphism is associated with higher endurance running performance in Japanese elite runners.
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ACE D/D genotype was associated with faster elite marathon speeds in Japanese runners; leaves open causal role and generalizability beyond this cross-sectional cohort.
Tobina et al. (2010) conducted an observational in Endurance running performance (n=372). ACE gene D/D genotype vs. ACE gene I/I genotype was evaluated on Marathon running speed (m/s) (p=0.005). The D/D genotype of the ACE gene was associated with significantly faster marathon running speeds compared to the I/I genotype (5.46 vs 5.31 m/s, p=0.005) among Japanese elite runners.
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