Why the study?
Does the ACE II genotype improve endurance performance in elite 400-m distance runners compared to ID and DD genotypes?
Does the ACE II genotype improve endurance performance in elite 400-m distance runners compared to ID and DD genotypes?
The ACE II genotype is associated with superior endurance performance and faster heart rate recovery in elite 400-m runners.
ACE II genotype was associated with superior endurance in elite runners; hypothesis-generating and should not yet inform training or selection.
A group of elite 400-m distance runners carrying different alleles of the polymorphic angiotensinconverting enzyme ( ACE ) gene participated in an experiment that included aerobic exercise accompanied by measurement of the heart rate (HR) before, during, and after the exercise. Upon determination of the genotype for the ACE gene, the athletes were divided into three subgroups, carrying the II, ID , and DD alleles of the ACE gene. All athletes performed the same exercise: 25 min of running at an HR of 165–170 beats/min. The runners with the II genotype ran a significantly ( p < 0.01) longer distance than the runners with the ID and DD genotypes. After the exercise, the HR recovery was the fastest in the runners with the II genotype.
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Voroshin et al. (2008) studied this question.
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