January 1, 2013Respiratory ResearchOpen Access

Initial presentation with pulmonary embolism in COPD patients was associated with a higher risk of VTE recurrence as PE (OR 2.04; 95% CI 1.11-3.72) and fatal PE compared to DVT alone.

Q: What is the clinical evidence from this study?

Study design: Cohort. Population: Venous thromboembolism and chronic obstructive pulmonary disease (n=4036). Intervention: Initial presentation with acute pulmonary embolism vs. Initial presentation with deep vein thrombosis alone. Primary outcome: VTE recurrence as pulmonary embolism (OR 2.04, 95% CI 1.11-3.72).

View Full Paper

Ask AI

Bookmark

Why the study?

Does initial presentation with acute PE compared to DVT alone increase the risk of adverse outcomes at 3 months in patients with VTE and COPD?

Population

4036 patients with venous thromboembolism and chronic obstructive pulmonary disease from the world-wide…

Comparison

Initial clinical presentation of acute pulmonary… vs Initial clinical presentation of deep vein…

Design

Cohort

Follow-up

3 months

Key result

Initial presentation with pulmonary embolism in COPD patients was associated with a higher risk of VTE recurrence as PE (OR 2.04; 95% CI 1.11-3.72) and fatal PE compared to DVT alone.

Authors

LBLaurent Bertoletti SQSara Quenet SLSilvy Laporte

Discussion

Member takes

Overview

May support closer surveillance in COPD patients with initial PE; leaves open optimal secondary prevention strategies.

Study Design

Type

Cohort (n=4,036)

Multicenter

Yes

Structured PICO

Does initial presentation with acute PE compared to DVT alone increase the risk of adverse outcomes at 3 months in patients with VTE and COPD?

Population

4,036 patients with chronic obstructive pulmonary disease and venous thromboembolism from the worldwide RIETE registry, followed for 3 months.

Exposure

Initial clinical presentation of acute pulmonary embolism (PE)

Comparator

Initial clinical presentation of deep vein thrombosis (DVT) alone

Outcome

Rate of pulmonary embolism (PE) recurrence, major bleeding, and death during the first 3 monthshard clinical

Main Result

Odds Ratio: 2.04 (95% CI 1.11–3.72)

In COPD patients with VTE, initial presentation with PE is associated with a significantly higher risk of recurrent PE and fatal PE at 3 months compared to DVT alone.

Cite This Study

Bertoletti et al. (2013) conducted a cohort in Venous thromboembolism and chronic obstructive pulmonary disease (n=4,036). Initial presentation with acute pulmonary embolism vs. Initial presentation with deep vein thrombosis alone was evaluated on VTE recurrence as pulmonary embolism (OR 2.04, 95% CI 1.11-3.72). Initial presentation with pulmonary embolism in COPD patients was associated with a higher risk of VTE recurrence as PE (OR 2.04; 95% CI 1.11-3.72) and fatal PE compared to DVT alone.

synapsesocial.com/papers/6ab70dafe8e89c0a8ec8b2b0 https://doi.org/10.1186/1465-9921-14-75

View Full Paper

Ask AI

Bookmark

January 1, 2013Respiratory ResearchOpen Access

Initial presentation with pulmonary embolism in COPD patients was associated with a higher risk of VTE recurrence as PE (OR 2.04; 95% CI 1.11-3.72) and fatal PE compared to DVT alone.

View Full Paper

Ask AI

Bookmark

Why the study?

Does initial presentation with acute PE compared to DVT alone increase the risk of adverse outcomes at 3 months in patients with VTE and COPD?

Population

4036 patients with venous thromboembolism and chronic obstructive pulmonary disease from the world-wide…

Comparison

Initial clinical presentation of acute pulmonary… vs Initial clinical presentation of deep vein…

Design

Cohort

Follow-up

3 months

Key result

Initial presentation with pulmonary embolism in COPD patients was associated with a higher risk of VTE recurrence as PE (OR 2.04; 95% CI 1.11-3.72) and fatal PE compared to DVT alone.

Authors

LBLaurent Bertoletti SQSara Quenet SLSilvy Laporte

Discussion

Member takes

Overview

May support closer surveillance in COPD patients with initial PE; leaves open optimal secondary prevention strategies.

Study Design

Type

Cohort (n=4,036)

Multicenter

Yes

Structured PICO

Does initial presentation with acute PE compared to DVT alone increase the risk of adverse outcomes at 3 months in patients with VTE and COPD?

Population

4,036 patients with chronic obstructive pulmonary disease and venous thromboembolism from the worldwide RIETE registry, followed for 3 months.

Exposure

Initial clinical presentation of acute pulmonary embolism (PE)

Comparator

Initial clinical presentation of deep vein thrombosis (DVT) alone

Outcome

Rate of pulmonary embolism (PE) recurrence, major bleeding, and death during the first 3 monthshard clinical

Main Result

Odds Ratio: 2.04 (95% CI 1.11–3.72)

In COPD patients with VTE, initial presentation with PE is associated with a significantly higher risk of recurrent PE and fatal PE at 3 months compared to DVT alone.

Cite This Study

synapsesocial.com/papers/6ab70dafe8e89c0a8ec8b2b0 https://doi.org/10.1186/1465-9921-14-75

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

View Full Paper

Ask AI

Bookmark