Key result
Pericardial fluid lipoprotein imbalance links to cholesterol crystal formation in cholesterol pericarditis.
Why the study?
The etiology of cholesterol pericarditis remains unknown despite previous hypotheses based on case reviews.
An imbalance in pericardial fluid lipoproteins may be responsible for the formation of cholesterol crystals in cholesterol pericarditis.
Answers are grounded in this paper and cite their sources.
Identifies pericardial cholesterol metabolism disorder as potential etiology; leaves open validation before any practice change.
Disorder of pericardial fluid cholesterol metabolism in cholesterol pericarditisTo the editor: Since Alexander's first report in 1919 (1), cholesterol pericarditis has been used to denote cases of chronic pericardial scintillating gold paint-like effusion with cholesterol crystal.Howeverits etiology remains unknown, although three hypotheses were introduced on the basis of the 47-cases review of Brawley et al (2).Wehave experienced this particular kind of case, and found an imbalance in the lipoprotein analysis of the pericardial fluid (PF), which is possibly responsible for cholesterol crystals.
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Noiri et al. (1991) conducted a letter in Cholesterol pericarditis. Lipoprotein imbalance was evaluated on Cholesterol crystal formation. An imbalance in the lipoprotein analysis of pericardial fluid was observed in a case of cholesterol pericarditis, suggesting a possible mechanism for cholesterol crystal formation.
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