Key result
A review of 9 cases of Kimura's disease and 5 cases of epithelioid hemangioma showed that these two disorders can be recognized as separate entities despite occasional clinicopathological overlap.
Observational (n=14)
Kimura's disease and epithelioid hemangioma exhibit distinct clinicopathological features, supporting their classification as separate entities.
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Clinicopathologic distinction of Kimura's disease from EH in small series may guide rare-case diagnosis; leaves open validation in larger cohorts.
The clinicopathological features of 9 cases of Kimura's disease and 5 cases of epithelioid hemangioma(EH) were reviewed. Patients with Kimura's disease presented with multiple or solitary large tumors occurring in the thigh, arms as well as parotid gland. Histologically, the lesions were characterized by numerous lymphoid follicles with proliferation of post-capillary venules lined by plump endothelium and a marked eosinophilic infiltration. Patients with EH were older than those with Kimura's disease and presented papular nodular lesions, less than 1 cm in size. Microscopically, there was proliferation of blood vessels lined by epithelioid endothelium with infiltration by lymphocytes and eosinophils. Although there may occasionally be clinicopathological overlap between Kimura's disease and EH, we consider that these two disorders can be recognized as separate entities.
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Ahn et al. (1990) conducted an observational in Kimura's disease and epithelioid hemangioma (n=14). Kimura's disease vs. Epithelioid hemangioma was evaluated on Clinicopathological features. A review of 9 cases of Kimura's disease and 5 cases of epithelioid hemangioma showed that these two disorders can be recognized as separate entities despite occasional clinicopathological overlap.
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