Key result
Novel mapping identifies true AF sources in only ~54% of patients with repetitive patterns.
Why the study?
Repetitive focal and rotational activation patterns are used as ablation targets for AF, but evidence is lacking that all detected targets are actual AF sources.
Does a novel mapping approach based on repetitiveness and entrainment capability identify probable sources of atrial fibrillation?
Population
13 patients with AF undergoing mapping with PentaRay catheter
Comparison
Repetitive focal and rotational activation patterns ranked by repetitiveness and entrainment capability
Design
Observational study using local activation time annotation of unipolar electrograms
Authors
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May warrant caution targeting repetitive AF patterns; leaves open validation of this technique in prospective trials.
Observational (n=13)
Does a novel mapping approach based on repetitiveness and entrainment capability identify probable sources of atrial fibrillation?
A novel mapping technique incorporating both repetitiveness and entrainment capability demonstrates that only a minority of focal or rotational patterns are likely to serve as true sources of atrial fibrillation.
Hermans et al. (2024) conducted an observational in Atrial fibrillation (n=13). Mapping technique based on repetitiveness and entrainment capability was evaluated on Identification of probable sources of AF. A novel mapping technique identified 10 probable AF source sites in 7 of 13 patients, showing that only a minority of repetitive focal or rotational patterns likely serve as actual sources of AF.
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