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December 1, 1950Archives of Internal Medicine

Studies on the Effects of Parenteral Quinidine Administration

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Key result

Parenteral quinidine lactate evaluation shows unspecified clinical effects in early descriptive study.

  • n=59

Why the study?

Parenteral quinidine therapy is needed for patients unable to take oral preparations or requiring rapid effect, but stable parenteral solutions have been lacking until recently.

Population

59 subjects divided into three groups: normal hearts, abnormal hearts with sinus rhythm, and a third group

Comparison

Effects of parenteral quinidine lactate administration

Design

Observational study of parenteral quinidine effects

Authors

HBHarris Blinder

Discussion

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Implication

Supports parenteral quinidine when oral intake impossible or rapidity needed; leaves open its role amid modern alternatives.

PICO

P
Population
59 subjects, including 22 with normal hearts and 15 with abnormal hearts with regular sinus rhythm, were studied to evaluate the effects of parenteral quinidine lactate.
I
Intervention / Comparator
Parenteral quinidine lactate

Cite This Study

Harris Blinder (1950) studied Normal and abnormal hearts (n=59). Parenteral quinidine lactate was evaluated. Parenteral quinidine lactate was administered to 59 subjects to evaluate its effects, though specific results are not reported in the truncated abstract.

synapsesocial.com/papers/6ab7663bf05009e2a0fb8c3fhttps://doi.org/10.1001/archinte.1950.00230180122011
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1STUDIES ON THE ACTION OF QUINIDINE IN MAN1943 · 29 citations
  2. 2Paroxysmal Ventricular Tachycardia: A Study of One Hundred and Seven Cases1950 · 184 citations