Key result
Coronary anatomy, physiology, and plaque morphology guide prognosis and targeted therapy in stable ischemic heart disease.
Why the study?
The optimal prognostic determinant among coronary anatomy, physiology, or plaque morphology for risk stratification in stable ischemic heart disease remains debated.
Does coronary anatomy, physiology, or plaque morphology best determine prognosis in patients with stable ischemic heart disease?
Does coronary anatomy, physiology, or plaque morphology best determine prognosis in patients with stable ischemic heart disease?
This review explores whether coronary anatomy, physiology, or plaque morphology is the best prognostic determinant to guide therapeutic strategies in stable ischemic heart disease.
May refine risk stratification algorithms in stable ischemic heart disease; leaves open which feature best drives prognosis and therapy.
Risk stratification in patients with stable ischemic heart disease is essential to guide treatment decisions. In this regard, whether coronary anatomy, physiology, or plaque morphology is the best determinant of prognosis (and driver an effective therapeutic risk reduction) remains one of the greatest ongoing debates in cardiology. In the present report, we review the evidence for each of these characteristics and explore potential algorithms that may enable a practical diagnostic and therapeutic strategy for the management of patients with stable ischemic heart disease.
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Ahmadi et al. (2016) conducted a review in Stable ischemic heart disease. Coronary anatomy, physiology, and plaque morphology was evaluated. This review evaluates coronary anatomy, physiology, and plaque morphology as prognostic determinants to guide management strategies in patients with stable ischemic heart disease.
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