Key result
Vaccination of piglets against PCV2 at 21 days of age resulted in lower mortality (6.33% vs 9%) and cull rates (11.33% vs 17.33%) compared to unvaccinated controls.
RCT (n=900)
Random sampling method
No
Absolute Event Rate: 6.33% vs 9%
May support early PCV2 vaccination to cut losses in piglets; leaves open need for randomized confirmation before wider adoption.
The aim of this research was to determine the effect of vaccination on the amount of antibody titers specific for PCV2, and to determine the effect of vaccination on characteristics of pig production. The first group (A) was vaccinated at 15 days old, the second (B) at 21 days old while the third (C) was the control group. Group B piglets attained the best results, so the vaccination of piglets at 21 days old would have an advantage compared to vaccination at 15 days old, although we note that at 15 days old, there is a far greater influence of maternal antibodies on the creation and development of immune responses in the piglets after vaccination.
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Stevančević et al. (2014) conducted an RCT in Porcine circovirus type 2 (PCV2) infection (n=900). PCV2 recombinant ORF2 subunit vaccine vs. Unvaccinated control was evaluated on Mortality. Vaccination of piglets against PCV2 at 21 days of age resulted in lower mortality (6.33% vs 9%) and cull rates (11.33% vs 17.33%) compared to unvaccinated controls.
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