Key result
CAD risk factors cluster into four distinct classes differing by sociodemographic profiles.
Why the study?
There was a need to identify latent classes based on major modifiable risk factors for coronary artery disease to understand heterogeneity in risk patterns.
Observational (n=2,022)
No
Identified four distinct latent classes of modifiable risk factors in patients newly diagnosed with coronary artery disease, highlighting the need for tailored prevention strategies.
May support tailored CAD prevention by risk clusters; leaves open whether latent-class approaches improve outcomes.
PURPOSE: This study aimed to identify latent classes based on major modifiable risk factors for coronary artery disease. METHODS: This was a secondary analysis using data from the electronic medical records of 2,022 patients, who were newly diagnosed with coronary artery disease at a university medical center, from January 2010 to December 2015. Data were analyzed using SPSS version 20.0 for descriptive analysis and Mplus version 7.4 for latent class analysis. RESULTS: Four latent classes of risk factors for coronary artery disease were identified in the final model: 'smoking-drinking', 'high-risk for dyslipidemia', 'high-risk for metabolic syndrome', and 'high-risk for diabetes and malnutrition'. The likelihood of these latent classes varied significantly based on socio-demographic characteristics, including age, gender, educational level, and occupation. CONCLUSION: The results showed significant heterogeneity in the pattern of risk factors for coronary artery disease. These findings provide helpful data to develop intervention strategies for the effective prevention of coronary artery disease. Specific characteristics depending on the subpopulation should be considered during the development of interventions.
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Ju et al. (2017) conducted an observational in Coronary artery disease (n=2,022). Major modifiable risk factors was evaluated on Latent classes of risk factors.
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