Key result
Higher admission neutrophil-to-lymphocyte ratio is linked to nearly 4-fold higher in-hospital complications in Takotsubo syndrome.
Why the study?
Hematological indices at admission may predict in-hospital complications in patients with Takotsubo syndrome, but this relationship was not well established.
Does admission neutrophil/lymphocyte ratio predict in-hospital complications in patients with Takotsubo syndrome?
Comparison
Higher neutrophil/lymphocyte ratio vs lower neutrophil/lymphocyte ratio at admission
Design
Multicenter prospective registry cohort study
Follow-up
In-hospital
Authors
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May inform risk stratification in Takotsubo syndrome; leaves open whether it improves outcomes or guides therapy.
Cohort (n=160)
Yes
Does admission neutrophil/lymphocyte ratio predict in-hospital complications in patients with Takotsubo syndrome?
Odds Ratio: 3.7 (95% CI 1.5–9.4)
Absolute Event Rate: 58% vs 22%
p-value: p=< .01
An elevated neutrophil/lymphocyte ratio at admission is an independent predictor of in-hospital complications in patients with Takotsubo syndrome.
Santoro et al. (2020) conducted a cohort in Takotsubo syndrome (n=160). Neutrophil/lymphocyte ratio (NLr) vs. Lower NLr values was evaluated on In-hospital complications (IHCs) (OR 3.7, 95% CI 1.5-9.4, p=< .01). Higher neutrophil/lymphocyte ratio at admission independently predicted in-hospital complications in patients with Takotsubo syndrome (OR 3.7; 95% CI 1.5-9.4; P<0.01).
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