Key result
Photoacoustic-enabled RF ablation visualizes atrial lesions and identifies gaps in real time.
Why the study?
Real-time feedback on lesion formation and post-treatment lesion assessment during catheter-based RF ablation could overcome procedural challenges related to ablation of underlying structures and lesion gaps.
Does real-time photoacoustic imaging allow visualization of radiofrequency ablation lesion formation and gaps in a preclinical porcine model?
Population
Porcine left atrium, both excised and intact in a passive beating heart ex-vivo
Comparison
Real-time visualization of lesion progression and continuity with photoacoustic imaging vs no real-time visualization
Design
Preclinical study using PA-enabled RF ablation catheter and intracardiac echography catheter
Authors
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PA imaging may enable real-time lesion monitoring during ablation; leaves open clinical validation before any practice change.
Does real-time photoacoustic imaging allow visualization of radiofrequency ablation lesion formation and gaps in a preclinical porcine model?
Photoacoustic imaging integrated with RF ablation catheters successfully visualizes lesion formation and gaps in real-time in a preclinical ex-vivo porcine model.
Iskander-Rizk et al. (2019) studied Aberrant conduction paths / Atrial intervention. Photoacoustic (PA) imaging with PA-enabled RF ablation catheter was evaluated on Real-time visualization of lesion progression and continuity. Photoacoustic imaging using a PA-enabled RF ablation catheter successfully visualized ablation lesions and identified lesion gaps in real-time in an ex-vivo porcine left atrium model.
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