Key result
Key hemodynamic measures correlate closely with the A2-OS interval in mitral stenosis.
Why the study?
The haemodynamic factors influencing the A2-OS interval in patients with mitral stenosis were not fully understood.
Observational (n=35)
The A2-OS interval in mitral stenosis correlates with left atrial V wave pressure, left ventricular systolic pressure, and mitral mean diastolic gradient, but not with mitral valve area.
Answers are grounded in this paper and cite their sources.
A2-OS correlates with select hemodynamics but not valve area in mitral stenosis; leaves open its role as a non-invasive surrogate.
Various haemodynamic measurements were correlated with the A2-OS interval in 35 patients with pure or predominant mitral stenosis. There was good correlation of left atrial V wave pressure, left ventricular systolic pressure, and mitral mean diastolic gradient with A2-OS. There was no significant correlation of mitral valve area with A2-OS. When the left ventricular pressure was arbitrarily assigned to one particular pressure (100 mm. Hg) correlations with all other variables improved. There was still no correlation of A2-OS interval with mitral valve area. These and other haemodynamic factors influencing the A2-OS interval are briefly discussed.
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EBRINGER et al. (1970) conducted an observational in pure or predominant mitral stenosis (n=35). Haemodynamic measurements was evaluated on Correlation with A2-OS interval. Left atrial V wave pressure, left ventricular systolic pressure, and mitral mean diastolic gradient correlated well with the A2-OS interval in patients with mitral stenosis.
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