Key result
Psoriasis was associated with a significantly higher mean epicardial fat area compared to matched controls (13.8 vs. 9.7 cm2; P=0.02).
Why the study?
Do patients with psoriasis have increased epicardial fat area and coronary artery calcium score compared to matched controls?
Population
76 subjects, comprising 38 patients with psoriasis and 38 controls matched for age and gender.
Comparison
Presence of psoriasis vs Controls matched for age and gender
Design
Case-control
Authors
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Should not yet change practice; leaves open whether epicardial fat mediates coronary risk in psoriasis.
Case-Control (n=76)
Do patients with psoriasis have increased epicardial fat area and coronary artery calcium score compared to matched controls?
Absolute Event Rate: 13.8% vs 9.7%
p-value: p=0.02
Patients with psoriasis have significantly higher epicardial fat area compared to matched controls, which is independently associated with coronary artery calcification.
Balcı et al. (2013) conducted a case-control in Psoriasis (n=76). Psoriasis vs. Controls without psoriasis was evaluated on Epicardial fat area (EFA) (p=0.02). Psoriasis was associated with a significantly higher mean epicardial fat area compared to matched controls (13.8 vs. 9.7 cm2; P=0.02).
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