The Relationship Between Microvascular Complications in Type 2 Diabetes with Mean Platelet Volume, Red Blood Cell Distribution Width, Neutrophile Lymphocyte Ratio

Objective: Diabetes mellitus (DM) is a complex syndrome caused by lack of insulin secretion and/or insulin resistance and emerges with high blood glucose levels, along with multiorgan involvement and characterized by micro/macro complications. Treatment process and complications of the disease are huge financial and moral problems for society as well as individuals. Material and Methods: Mean platelet volume (MPV), red cell distribution width (RDW), glycosylated hemoglobin (HbA1c), neutrophil and lymphocyte counts and ratio (Neutrophil lymphocyte ratio), microvascular complications (neuropathy, retinopathy and nepropathy) of 60 patiens diagnosed as diabetes and 60 healty individuals have been evaluated retrospectively. Results: In this study, we evaluated relationship between microvascular compliations with RDW, MPV, NLR. There was statistically significant difference between nephropathy with RDW, MPV, and NLR (respectively p: 0.008, p: 0.014 and p: 0.017). There was statistically significant difference between retinopathy with RDW and MPV (respectively p: 0.036 and p: 0.019), no statistically difference with NLR (p: 0.129). Within neuropathy, there was statistically significant difference between neuropathy with RDW and NLR (respectively p: 0.001 and p: 0.045), no relationship with MPV (p: 0.157). Conclusion: RDW, MPV, NLR values included in a simple laboratory test such as a hemogram are cost-effective parameters to demonstrate diabetic microvascular complications.