What is the clinical evidence from this study?

Study design: Case Report. Population: Eosinophilic myocarditis (n=1). Intervention: Steroid treatment. Primary outcome: Clinical features, total eosinophil count, and serum ECP.

What does this research mean for the field?

Steroid treatment normalizes total eosinophil count and serum eosinophil cationic protein (ECP) levels, leading to clinical improvement in eosinophilic myocarditis. Novelty: ClaimNovelty.CONFIRMATORY. Consensus alignment: ConsensusAlignment.SUPPORTS_CONSENSUS.

June 1, 1999HeartOpen Access

Eosinophilic myocarditis associated with dense deposits of eosinophil cationic protein (ECP) in endomyocardium with high serum ECP

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Key result

Steroids normalize eosinophil markers and resolve clinical features in eosinophilic myocarditis.

Why the study?

Eosinophilia may cause cardiac damage, and the role of eosinophil degranulation and serum ECP as diagnostic and treatment indicators in eosinophilic myocarditis needed confirmation.

Comparison

Steroid treatment effect on eosinophil count and serum ECP

Design

Case report

Authors

MAMizuhiro ArimaInternational Goodwill Hospital TKTakako Kanoh

Discussion

Member takes

Overview

Single case links high ECP to eosinophilic myocarditis; hypothesis-generating for biomarker role, needs prospective validation.

Study Design

Type

Case Report (n=1)

Structured PICO

Population

A 27-year-old woman with NYHA class III congestive heart failure and eosinophilic myocarditis.

Intervention

Steroid treatment

Outcome

Normalization of total eosinophil count and serum ECP, and improvement in clinical features

Serum eosinophil cationic protein (ECP) levels may serve as a reliable biomarker for the diagnosis and treatment monitoring of eosinophilic myocarditis.

Cite This Study

Arima et al. (1999) conducted a case report in Eosinophilic myocarditis (n=1). Steroid treatment was evaluated on Clinical features, total eosinophil count, and serum ECP. Steroid treatment normalized total eosinophil count and serum ECP levels, leading to satisfactory improvement in clinical features of eosinophilic myocarditis.

synapsesocial.com/papers/6ab8c6cd12a368ca8ffcfbd9 https://doi.org/10.1136/hrt.81.6.669

Topics

Myocarditis

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June 1, 1999HeartOpen Access

Eosinophilic myocarditis associated with dense deposits of eosinophil cationic protein (ECP) in endomyocardium with high serum ECP

View Full Paper

Ask AI

Bookmark

Key result

Steroids normalize eosinophil markers and resolve clinical features in eosinophilic myocarditis.

Why the study?

Eosinophilia may cause cardiac damage, and the role of eosinophil degranulation and serum ECP as diagnostic and treatment indicators in eosinophilic myocarditis needed confirmation.

Comparison

Steroid treatment effect on eosinophil count and serum ECP

Design

Case report

Authors

MAMizuhiro ArimaInternational Goodwill Hospital TKTakako Kanoh

Discussion

Member takes

Overview

Single case links high ECP to eosinophilic myocarditis; hypothesis-generating for biomarker role, needs prospective validation.

Study Design

Type

Case Report (n=1)

Structured PICO

Population

A 27-year-old woman with NYHA class III congestive heart failure and eosinophilic myocarditis.

Intervention

Steroid treatment

Outcome

Normalization of total eosinophil count and serum ECP, and improvement in clinical features

Serum eosinophil cationic protein (ECP) levels may serve as a reliable biomarker for the diagnosis and treatment monitoring of eosinophilic myocarditis.

Cite This Study

synapsesocial.com/papers/6ab8c6cd12a368ca8ffcfbd9 https://doi.org/10.1136/hrt.81.6.669

Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

Topics

Myocarditis

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