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September 28, 2026Russian Journal of Bioorganic Chemistry

Synthesis, Molecular Docking, and ADMET Evaluation of Novel Quinazolinone-Coumarin Hybrid Derivatives as Dual Inhibitors of Urease and Acetylcholinesterase

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Authors

NÇNedime ÇalışkanGAGülay AkyüzFİFatih İslamoğlu

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Çalışkan et al. (2026) studied this question.

synapsesocial.com/papers/6ab9b44a7822ec8fc3d8dba5https://doi.org/10.1134/s1068162026600650
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  1. 1Synthesis and Characterization of Some New 2,3-Disubstituted Quinazolin-4(3H)-one Compounds, Investigation of Urease, and AChE Inhibition Properties, Molecular, and Docking Study2024 · 3 citations
  2. 2Synthesis, in vitro and in silico investigations of coumarin-benzamide hybrid molecules as urease inhibitors2025
  3. 3Discovery of new acetylcholinesterase inhibitors derived from quinazolinones: synthesis, in vitro, and molecular docking study2025
  4. 4Coumarin Derivatives as Potent Urease Inhibitors: In Vitro Evaluation, and Molecular Docking Studies2026
  5. 5Quinindoline-Based Hybrid Compounds as New Inhibitors of Acetylcholinesterase: An In Vitro and Molecular Dynamics Simulations Study2024