Key result
BP-to-height ratio accurately detects hypertension in Black adolescents with an AUC of ~0.97.
Why the study?
Current methods of detection of childhood hypertension are cumbersome and contribute to under-diagnosis, necessitating simpler diagnostic tools.
Does blood pressure to height ratio accurately detect prehypertension and hypertension in adolescents?
Cross-Sectional (n=2,364)
Does blood pressure to height ratio accurately detect prehypertension and hypertension in adolescents?
Effect estimate: AUC 0.954-0.978 for hypertension
Blood pressure to height ratio is a highly sensitive and accurate screening tool for detecting hypertension in adolescents.
May support adolescent hypertension screening; hypothesis-generating in cross-sectional data, requiring prospective validation before adoption.
BACKGROUND: Current methods of detection of childhood hypertension are cumbersome and contribute to under-diagnosis hence, the need to generate simpler diagnostic tools. The blood pressure to height ratio has recently been proposed as a novel screening tool for prehypertension and hypertension in some populations. We evaluated its applicability in our environment. MATERIALS AND METHODS: The weights, heights, and blood pressure measurements of 2364 apparently healthy adolescents were determined. Sex-specific systolic and diastolic blood pressure to height ratios (SBPHR) and (DBPHR) were calculated, and their ability to detect prehypertension and hypertension was determined using receiver operating curves. Discriminatory ability was measured by the area under the curve (AUC) and optimal cutoff points along the curve were determined. P < 0.05 was considered statistically significant. RESULTS: The SBPHR and DBPHR were similar across all age groups and sexes. The AUC of SBPHR and DBPHR for diagnosing prehypertension and hypertension by sex was >0.95 for both diastolic and systolic hypertension in both sexes. It ranged between 0.803 and 0.922 for prehypertension and 0.954-0.978 for hypertension indicating higher accuracy for hypertension. Sensitivity was higher for systolic and diastolic hypertension (90-98%) compared with prehypertension (87-98%). Specificity was lower than sensitivity across all categories of hypertension and prehypertension (0.64-0.88%) though higher for hypertension (0.75-0.88) compared with prehypertension (0.64-0.75). CONCLUSION: BPHR is a useful screening tool for prehypertension and hypertension in black adolescents. Accuracy increased with higher degrees of hypertension.
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Ladapo et al. (2016) conducted a cross-sectional in Prehypertension and hypertension (n=2,364). Blood pressure to height ratio (BPHR) was evaluated on Diagnostic accuracy (AUC) for prehypertension and hypertension (AUC 0.954-0.978 for hypertension). Blood pressure to height ratio accurately detected hypertension in black adolescents, with an area under the curve of 0.954-0.978 and sensitivity of 90-98%.
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