Key result
The authors discuss the proposal that pericyte dysfunction could mechanistically link pulmonary vascular remodeling and myocardial injury in systemic autoimmune disease.
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The authors agree that pericyte dysfunction could mechanistically link pulmonary vascular remodeling and myocardial injury in systemic sclerosis.
We thank Dr. Sbarra and colleagues for extending our review's framework to systemic sclerosis (SSc)-associated cardiopulmonary disease.Their proposal-that pericyte dysfunction could mechanistically link pulmonary vascular remodeling and myocardial injury in systemic autoimmune disease-is well grounded in what is now known about cardiac pericyte biology, and we would like to elaborate on several points of convergence and caution.
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Vinicio de Jesús Pérez (2026) conducted a letter in Systemic sclerosis (SSc)-associated cardiopulmonary disease. The authors discuss the proposal that pericyte dysfunction could mechanistically link pulmonary vascular remodeling and myocardial injury in systemic autoimmune disease.
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