March 1, 1997Journal of Cardiopulmonary Rehabilitation
Predictors of Exercise Capacity and Adaptability to Training in Patients With Coronary Artery Disease
Key result
Six-month exercise training improves exercise capacity regardless of LVEF, with noncardiac factors explaining ~50% of peak VO2.
- n=171
Why the study?
Systolic left ventricular dysfunction is a weak predictor of exercise tolerance in patients with chronic congestive heart failure, necessitating identification of other predictors in coronary artery disease patients.
Does a medically supervised exercise training program improve exercise capacity in patients with coronary artery disease regardless of their degree of left ventricular dysfunction?
Comparison
Effort tolerance and adaptability to training across different levels of left ventricular dysfunction
Design
Cohort study of medically supervised exercise training program
Follow-up
6 months
Authors
Discussion
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Implication
Noncardiac factors may limit exercise capacity in HF; leaves open optimal integration of exercise training into care pathways.
Study Design
Type
Cohort (n=171)
Structured PICO
Does a medically supervised exercise training program improve exercise capacity in patients with coronary artery disease regardless of their degree of left ventricular dysfunction?
P
Population
171 patients with documented coronary artery disease and various degrees of left ventricular dysfunction enrolled in a 6-month medically supervised exercise training program.
E
Exposure
Medically supervised exercise training program for 6 months
O
Outcome
Predictors of effort tolerance and adaptability to training (measured by peak oxygen uptake, ventilatory threshold, and treadmill time to exhaustion)surrogate
Noncardiac factors are better predictors of effort tolerance than left ventricular function in patients with coronary artery disease, and patients derive similar benefits from exercise training regardless of their degree of LV dysfunction.
Cite This Study
DIGENIO et al. (1997) conducted a cohort in Coronary artery disease (n=171). Medically supervised exercise training program was evaluated on Peak oxygen uptake, ventilatory threshold, and treadmill time to exhaustion. Noncardiac factors explained 50% of the variation in peak oxygen uptake, and a 6-month exercise program significantly improved exercise capacity regardless of left ventricular dysfunction.