Key result
Ventriculo-arterial coupling correlates with peak VO2 in reduced LVEF CAD, and arterial compliance in normal LVEF.
Why the study?
Do baseline cardiovascular mechanics predict exercise capacity in patients with coronary artery disease?
Population
50 consecutive patients with coronary artery disease referred to cardiac rehabilitation. Excluded: non-sinus…
Design
Cohort
Authors
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May support mechanics-based prediction of exercise capacity in CAD; hypothesis-generating and requires prospective validation before clinical use.
Observational (n=50)
Do baseline cardiovascular mechanics predict exercise capacity in patients with coronary artery disease?
Effect estimate: r=0.410
p-value: p=0.04
Baseline cardiovascular mechanics, specifically ventriculo-arterial coupling in reduced LVEF and arterial compliance in normal LVEF, correlate with exercise capacity in CAD patients.
Aslanger et al. (2015) conducted an observational in Coronary artery disease (n=50). Baseline cardiovascular mechanics was evaluated on Peak oxygen consumption (VO2) (r=0.410, p=0.04). Baseline ventriculo-arterial coupling correlated with peak VO2 in CAD patients with reduced LVEF (r=0.410, p=0.04), while arterial compliance correlated in those with normal LVEF (r=0.467, p=0.01).
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