Key result
Corticosteroid therapy resolves fulminant necrotizing eosinophilic myocarditis without residual myocardial damage.
Why the study?
Necrotizing eosinophilic myocarditis is a rare but potentially fatal condition that requires prompt recognition and treatment.
Case Report (n=1)
This case highlights the utility of cardiac magnetic resonance imaging and endomyocardial biopsy in the early diagnosis and monitoring of acute fulminant necrotizing eosinophilic myocarditis successfully treated with corticosteroids.
May support CMR-guided steroid therapy in suspected necrotizing eosinophilic myocarditis; leaves open need for prospective validation.
Necrotizing eosinophilic myocarditis is a rare but potentially fatal condition that requires prompt recognition and treatment. We describe a case of a young athlete presenting with chest pain and breathlessness, with evidence of rapidly deteriorating cardiac function. The condition was successfully treated with corticosteroids, with no evidence of residual myocardial damage. This is the first reported case to demonstrate the utility of cardiac magnetic resonance imaging for diagnosis and monitoring response to treatment. It also highlights the value of endomyocardial biopsy in establishing a tissue diagnosis in cases of fulminant myocarditis, in order to direct treatment appropriately.
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Callan et al. (2017) conducted a case report in Acute Fulminant Necrotizing Eosinophilic Myocarditis (n=1). Corticosteroids was evaluated. Corticosteroid therapy successfully treated acute fulminant necrotizing eosinophilic myocarditis in a young athlete, with no evidence of residual myocardial damage.
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