Key result
AF prevalence rises ~13% per five years from 1960 to 1989 in ischemic stroke patients and controls.
Why the study?
There is limited data on secular trends in the prevalence of atrial fibrillation over time in clinical practice.
Population
1,871 incident ischemic stroke cases and age- and gender-matched controls in Rochester, Minnesota from 1960 to 1989
Comparison
Stroke cases vs matched population controls
Design
Longitudinal case-control study
Follow-up
30 years
Authors
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Case-control study observes elevated atrial fibrillation prevalence in incident stroke patients, highlighting cardiac arrhythmia as a major stroke risk factor.
Case-Control (n=3,742)
No
Odds Ratio: 1.13 (95% CI 1.05–1.22)
p-value: p=0.001
Tsang et al. (2003) conducted a case-control in Ischemic stroke (n=3,742). Calendar time vs. Earlier calendar time was evaluated on Prevalence of atrial fibrillation (OR 1.13, 95% CI 1.05-1.22, p=0.001). The prevalence of atrial fibrillation increased significantly from 1960 to 1989 in both ischemic stroke patients (OR per 5 years 1.13; 95% CI 1.05-1.22) and matched controls.
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