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June 15, 2009Clinical Management IssuesOpen Access

Beta-blockers in chronic heart failure in elderly patient

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Key result

Beta-blockers show efficacy and tolerability in elderly chronic heart failure patients despite widespread underuse.

Why the study?

Beta-blockers are effective and well tolerated in elderly patients with chronic heart failure but are substantially underutilized in clinical practice.

Are beta-blockers effective and well tolerated in elderly patients with chronic heart failure?

Population

Elderly patients with chronic heart failure

Comparison

Beta-blockers versus no beta-blockers or other treatments

Design

Review of published randomized trials and observational studies

Authors

ABAlberto De BernardiUniversity of Siena

Discussion

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Member takes

Overview

Beta-blockers remain underutilized in elderly CHF despite supporting evidence; leaves open optimal implementation strategies for practice and trials.

Structured PICO

Are beta-blockers effective and well tolerated in elderly patients with chronic heart failure?

P
Population
Elderly patients with chronic heart failure (CHF)
I
Intervention
Beta-blockers

Despite evidence of efficacy and tolerability, beta-blockers remain underutilized in elderly patients with chronic heart failure.

Cite This Study

Alberto De Bernardi (2009) conducted a review in Chronic heart failure (CHF). Beta-blockers was evaluated. A review of published trials suggests that beta-blockers are effective and well tolerated in elderly patients with chronic heart failure, despite being substantially underutilized in clinical practice.

synapsesocial.com/papers/6abe585db297982ddf6e5eb0https://doi.org/10.7175/cmi.v3i2.553

Topics

Heart failureHFrEF treatment
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Treatment of chronic heart failure with β adrenergic blockade beyond controlled clinical trials: the BRING-UP experience2003 · 84 citations
  2. 2Results From Post-Hoc Analyses of the CIBIS II Trial: Effect of Bisoprolol in High-Risk Patient Groups with Chronic Heart Failure2001 · 191 citations
  3. 3Perindopril for Elderly People with Chronic Heart Failure: The PEP-CHF Study1999 · 254 citations
  4. 4Safety and efficacy of carvedilol in very elderly diabetic patients with heart failure2007 · 13 citations
  5. 5The epidemiology of heart failure: The Framingham Study1993 · 2,263 citations