Why the study?
Scrub typhus has wide organ involvement including cardiac manifestations, but rare electrocardiographic changes have not been well described.
Case Report (n=1)
Scrub typhus can manifest with rare, reversible electrocardiographic abnormalities such as second-degree AV block and Osborn waves, which resolve promptly with appropriate antibiotic therapy.
Alerts clinicians to reversible conduction defects in endemic scrub typhus; extends sparse case-level evidence on ECG manifestations.
Scrub typhus (ST) has wide organ system involvement, but cardiac involvement is paramount in this spectrum due to early hemodynamic compromise. Various forms of cardiac involvement have been described in the literature, but we are describing rare electrocardiographic changes in the ST infection. A young male presented in our emergency department with complaints of restlessness and vomiting of 2 days' duration. The patient was having stable vitals on presentation, but his electrocardiogram (ECG) demonstrated second-degree atrioventricular block type 1 (also known Mobitz 1) and Osborn wave in the precordial leads. Further, he was having thrombocytopenia and eventually diagnosed with ST. For this, appropriate antibiotic treatment was given, which led to considerable symptomatic improvement and reversal of the ECG changes.
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Gupta et al. (2022) conducted a case report in Scrub typhus with electrocardiographic disturbance (n=1). Doxycycline was evaluated on Clinical and electrocardiographic recovery.
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