Key result
Pharmacological autonomic blockade reveals swallowing-induced tachycardia involves variable sympathetic and vagal mechanisms.
Why the study?
Swallowing-induced tachycardia and its autonomic nervous system mechanisms are not well characterized, limiting tailored treatment approaches.
Case Report (n=3)
No
Answers are grounded in this paper and cite their sources.
Swallowing tachycardia mechanisms appear heterogeneous; hypothesis-generating and should not yet change practice.
Three cases are reported who have short runs of atrial premature contractions (APCs) induced by swallowing and cough. The occurrence of the APCs were affected by autonomic nervous system in all cases. The precipitating factor is considered to be the increase of vagal tone in case 1, sympathetic tone in case 2 and both of them in case 3. The autonomic mechanism of swallowing-induced tachycardia could be divided into three categories and the treatment of these arrhythmias might be different in each group. Pharmacological autonomic blockade with atropine and propranolol is useful to reveal the underlying autonomic mechanisms.
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Shirayama et al. (1989) conducted a case report in Swallowing-induced tachycardia (n=3). Pharmacological autonomic blockade (atropine and propranolol) vs. Baseline (unblocked state) was evaluated on Suppression of swallowing-induced arrhythmias. Pharmacological autonomic blockade with atropine and propranolol revealed that swallowing-induced tachycardia can be driven by increased vagal tone, sympathetic tone, or a combination of both.
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