Key result
Current medical management of HFrEF in Cameroon is suboptimal, with only 4% of patients on ACE inhibitors and 3.4% on beta-blockers reaching the maximum ESC 2016 recommended doses.
Why the study?
The current treatment of chronic heart failure with reduced ejection fraction in Cameroonian patients and its adherence to ESC 2016 recommendations was not described.
Cross-Sectional (n=87)
Yes
Answers are grounded in this paper and cite their sources.
The medical management of HFrEF in Cameroon is suboptimal, with low rates of guideline-directed medical therapy at target doses compared to ESC 2016 recommendations.
ABSTRACTPurpose.To describe the current treatment of chronic heart failure with reduced ejection fraction in a self-selected population of Cameroonian patients and compare it with the recommendations of the European Society of Cardiology 2016 (ESC 2016). Materials and Methods. In a cross-sectional study, we included subjects with chronic heart failure with reduced ejection fraction from December 2018 to May 2018 in four hospital settings in Yaoundé, Cameroon. For each study participant, we collected clinical and para-clinical data related to drug and non-drug treatment. All these, through questioning and using the medical records of patients seen in an outpatient cardiology consultation. Results. A total of 87 patients, including 46 women and 41 men, participated in the study, with a mean age of 63.97 ± 13 years. The ejection fraction of our subjects ranged from 16 - 39%. 57% of the patients were on Angiotensin-converting enzyme inhibitors (ACEI), 22% on Angiotensin II receptor blockers (ARAII), 68% on beta-blockers, and 26% on potassium-sparing diuretics, 87% on loop diuretics, 11% on thiazide diuretics and 24% on digoxin. 59.77% were under the double combination ACEI and beta-blockers, 12.64% under triple combination ACEI, beta-blockers and diuretics. The maximum ESC 2016 recommended dose was reached in 4% of patients on ACEI, 3.38% on beta-blockers, 26.08% on potassium-sparing diuretics, 84.21% on loop diuretics and 100% on thiazide diuretics. 3.44% were taking contraindicated drugs such as non-steroidal anti-inflammatory drugs (NSAIDs). Patients consuming more than 5g/day of salt was found in 29% of patients, alcohol consumption in 29%, and tobacco consumption in 7%. Conclusion. The treatment of chronic heart failure with reduced ejection fraction is suboptimal in Cameroon. Based on these findings, there is a need for courses for health personal involved in managing these patients to regularly update and, above all, promote therapeutic education for these patients.RÉSUMÉObjectif. Décrire le traitement de l'insuffisance cardiaque chronique à fraction d'éjection réduite dans une population de patients camerounais et le comparer aux recommandations de la Société Européenne de Cardiologie 2016 (ESC 2016). Matériel et méthodes. Dans une étude transversale, nous avons inclus des sujets atteints d'insuffisance cardiaque chronique avec fraction d'éjection réduite de décembre 2018 à mai 2018 dans quatre établissements hospitaliers de Yaoundé, au Cameroun. Pour chaque sujet, nous avons collecté des données cliniques et paracliniques liées au traitement médicamenteux et non médicamenteux. Résultats. Sur un total de 87 patients, 46 femmes et 41 hommes, avaient un âge moyen de 63,97±13 ans. La fraction d'éjection de nos sujets variait de 16 à 39%. 57% des patients étaient sous inhibiteurs de l'enzyme de conversion de l'angiotensine (IEC), 22% sous antagonistes des récepteurs de l'angiotensine II (ARAII), 68% sous bêtabloquants et 26% sous diurétiques d'épargne potassique, 87% sous diurétiques de l'anse, 11% sous diurétiques thiazidiques et 24% sous digoxine. 59,77% étaient sous la double association IEC-bêtabloquants, 12,64 % sous la triple association IEC-bêtabloquants-diurétiques. La dose maximale recommandée par l'ESC 2016 a été atteinte chez 4% des patients sous IEC, 3,38% sous bêtabloquants, 26,08% sous diurétiques épargneurs de potassium, 84,21% sous diurétiques de l'anse et 100 % sous diurétiques thiazidiques. 3,44% prenaient des médicaments contre-indiqués tels que les anti-inflammatoires non stéroïdiens (AINS). Des patients consommant plus de 5 g/jour de sel ont été retrouvés dans 29 % des cas, une consommation d'alcool chez 29% et une consommation de tabac chez 7%. Conclusion. Le traitement de l'insuffisance cardiaque chronique avec fraction d'éjection réduite est sous-optimal au Cameroun. Il existe un besoin en formations continues des personnels de santé impliqués dans la prise en charge de ces patients en plus de favoriser l'éducation thérapeutique de ces patients.
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Nadège et al. (2022) conducted a cross-sectional in chronic heart failure with reduced ejection fraction (n=87). Current medical management vs. ESC 2016 recommendations was evaluated on Current treatment patterns and adherence to ESC 2016 recommendations. Current medical management of HFrEF in Cameroon is suboptimal, with only 4% of patients on ACE inhibitors and 3.4% on beta-blockers reaching the maximum ESC 2016 recommended doses.
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