Separating Ideal-Circuit Structure from Hardware-Dependent Deviations in a Fixed 35-Qubit Diagnostic Circuit on IBM Heron Processors

H. Billah and M.M.H. Sarker contributed equally to this work. Interpreting a fixed quantum circuit's output as evidence of a hardware effect requires ruling out two things usually conflated with it: finite-sample fluctuation, and structure already present in the circuit's own noiseless output. Less commonly checked is a third: whether the reference circuit compared against is the one actually executed, once compiler-level qubit routing is accounted for. We execute a fixed 35-qubit, 243-gate diagnostic circuit on IBM Heron-family hardware (three runs, two backends) and show this third check is essential: the routed circuit submitted to hardware has different noiseless predictions than the logical circuit intended, for several qubits. Against the correct, routed-circuit reference, the aggregate deviation is significant in two of three runs, and four registers (0, 9, 14, 27) show a significant output-probability deviation in every run — though we distinguish a high-confidence subset, {0, 9, 27}, with tightly time-matched calibration, from qubit 14, included only on an exploratory basis given its calibration was retrieved roughly two weeks post-execution. Same-backend replicates correlate more strongly by the Pearson measure, though a rank-based (Spearman) test shows this gap does not survive at the level of register ordering, indicating substantial leverage from a small number of registers rather than a broadly robust pattern; these three executions also share a byte-identical payload and are not independent replications in the strictest sense. The mechanism is only partially resolved: independent single-qubit readout error and raw gate count are ruled out as complete explanations for most of these registers, but the simplest version of the leading hypothesis for the single most-affected register does not reproduce the observed cross-backend pattern even with live, backend-specific timing data. A second, structurally different circuit validated only in simulation calibrates the statistical procedure's behavior under one synthetic noise model; it does not itself establish generality to real hardware, and the specific register set found here should not be expected to generalize beyond this study. Note on scope: this is a methodology and case-study contribution centered on executed-circuit references for fixed-circuit diagnostics, not a characterization of IBM Heron hardware in general or a randomized-benchmarking experiment in the formal sense. Supporting data, the routed OpenQASM circuits, raw measurement counts, and analysis code for this study are available on request from the corresponding author. Affiliation: Sonicium Quantum Lab Ltd., Dhaka, Bangladesh.