Key result
Corticosteroids plus cyclophosphamide restores LV systolic function within ~2 months in Churg-Strauss Loeffler endocarditis.
Why the study?
Cardiac involvement is a major cause of morbidity and mortality in Churg-Strauss syndrome, but thrombotic phase of Loeffler's endocarditis associated with heart failure in CSS patients has been rarely reported.
Case Report (n=1)
No
Answers are grounded in this paper and cite their sources.
May support corticosteroids plus cyclophosphamide in Churg-Strauss-associated Loeffler endocarditis; leaves open confirmation in prospective studies.
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Seo et al. (2010) conducted a case report in Loeffler's endocarditis associated with Churg-Strauss syndrome (n=1). Methylprednisolone, cyclophosphamide, and warfarin was evaluated on Clinical and echocardiographic improvement. Treatment with corticosteroids and cyclophosphamide led to marked clinical improvement and recovery of left ventricular systolic function within 2 months in a patient with Loeffler's endocarditis associated with Churg-Strauss syndrome.
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