Right Ventricular Isovolumic Acceleration in Children with Patent Ductus Arteriosus: Short and Mid-term Follow-up after Percutaneous Device Closure

Objective: We aimed to assess the association of right ventricular acceleration during isovolumic contraction (RVIVA) to functional recovery after device closure of patent ductus arteriosus (PDA). Methods: 84(7.5+6.8 year; 49 female ) patients who underwent device closure of PDA were evaluated with conventional and tissue Doppler echocardiography pre closure, at 24 hours and at 6 months post closure to assess RVIVA, myocardial performance index (MPI). Brain natreuretic peptide (BNP) was assessed pre closure and 6 months post closure Results: RVIVA was significantly decreased in children with PDA, while other conventional Echo Doppler parameters were comparable to controls. Following closure of PDA, RVIVA was significantly increased (P 2.4 m/s was the best cutoff value in predicting functional recovery after percutaneous closure of PDA. Conclusion: Measurement of RVIVA in patients with PDA specially those presented late are important to differentiate high- and low-risk groups in terms of prognosis.. RVIVA might be considered a useful indicator for functional recovery after device closure of PDA