Key result
Obstructive sleep apnea is linked to ~2.6-fold higher stroke prevalence in type 2 diabetes.
Why the study?
Type 2 diabetes mellitus and obstructive sleep apnea are common comorbid conditions implicated in cardiovascular disease, but their association in overweight and obese adults with T2DM is unclear.
Comparison
Obstructive sleep apnea severity measured by apnea-hypopnea index
Design
Cross-sectional ancillary study to the Look AHEAD trial
Authors
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AHI linked to prevalent stroke (not CHD) in obese T2DM; hypothesis-generating for OSA-CVD links, prospective studies required before screening implications.
Cross-Sectional (n=305)
Odds Ratio: 2.57 (95% CI 1.03–6.42)
Rice et al. (2012) conducted a cross-sectional in Type 2 diabetes mellitus and overweight/obesity (n=305). Obstructive sleep apnea (apnea-hypopnea index) vs. Lower apnea-hypopnea index was evaluated on Prevalent stroke (OR 2.57, 95% CI 1.03-6.42). Obstructive sleep apnea (measured by AHI) was significantly associated with prevalent stroke (OR 2.57; 95% CI 1.03-6.42) in overweight and obese adults with type 2 diabetes.
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