Key result
PulseSelect PFA achieves near-zero fluoroscopy PVI and posterior wall isolation in common inferior PV anatomy.
Why the study?
A common inferior pulmonary vein (CIPV) variant poses significant challenges for atrial fibrillation ablation due to proximity to the esophagus and risk of pulmonary vein stenosis, and no prior reports have described use of the PulseSelect pulsed-field ablation catheter in this context.
Does pulsed-field ablation using the PulseSelect catheter achieve successful isolation in a patient with persistent AF and a common inferior pulmonary vein?
Case Report (n=1)
No
Does pulsed-field ablation using the PulseSelect catheter achieve successful isolation in a patient with persistent AF and a common inferior pulmonary vein?
Pulsed-field ablation using the PulseSelect catheter is feasible, safe, and effective for treating persistent AF in patients with challenging anatomy such as a common inferior pulmonary vein, allowing for near-zero fluoroscopy.
Supports feasibility of near-zero fluoroscopy PulseSelect PFA in CIPV; leaves open generalizability pending larger studies.
Catheter ablation has become the gold standard treatment for drug-refractory symptomatic atrial fibrillation (AF), with pulmonary vein isolation (PVI) serving as the cornerstone of the procedure. However, 23% to 38% of patients undergoing AF ablation exhibit pulmonary vein anomalies, among which a common inferior pulmonary vein (CIPV) variant is particularly rare (0.9%–1.5%).1
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Kumazawa et al. (2025) conducted a case report in Persistent atrial fibrillation with common inferior pulmonary vein (n=1). Pulsed-field ablation (PulseSelect catheter) was evaluated on Successful pulmonary vein isolation and posterior wall isolation. Pulsed-field ablation using the PulseSelect catheter successfully achieved pulmonary vein and posterior wall isolation with near-zero fluoroscopy in a patient with a common inferior pulmonary vein.
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