Key result
Atrial septal pacing shows no benefit over high right atrial pacing for AF burden.
Why the study?
Permanent right atrial pacing may cause delayed interatrial conduction and predispose to atrial fibrillation, motivating evaluation of atrial septal pacing as an alternative.
RCT (n=43)
p-value: p=NS
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Does not support septal pacing to reduce AF; leaves open whether lead position affects outcomes in device patients.
Hakacova et al. (2007) conducted an RCT in Recurrent paroxysmal atrial fibrillation (n=43). Atrial septal pacing vs. High right atrial pacing was evaluated on Atrial fibrillation duration and number of episodes (mode-switching episodes or AF burden) (p=NS). Atrial septal pacing showed no significant difference compared with high right atrial pacing in atrial fibrillation duration and number of episodes (P = NS).
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