Key result
Remote pacemaker interrogation is evaluated against transtelephonic monitoring for earlier actionable event diagnosis in PREFER.
Why the study?
Remote monitoring systems have not been studied for pacemaker patients despite their potential to provide earlier diagnosis of clinically actionable events compared to transtelephonic monitoring and office visits.
Population
980 pacemaker patients enrolled at 50 US centers
Comparison
Remote interrogation using Medtronic CareLink versus transtelephonic monitoring plus periodic in-person evaluations
Design
Prospective, randomized, parallel, unblinded, multicenter, open-label clinical trial
Follow-up
12 months planned
Authors
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May accelerate diagnosis of actionable events in paced patients; leaves open impact on hard clinical outcomes.
RCT (n=980)
Open-label
Permutated block randomization (2:1)
Yes
Chen et al. (2008) conducted an RCT in Pacemaker patients (n=980). Remote pacemaker interrogation (Medtronic CareLink Network) vs. Transtelephonic monitoring (TTM) and routine office visits was evaluated on Rate of first diagnosis of clinically actionable events. Remote pacemaker interrogation is being evaluated in the PREFER trial to determine if it allows earlier diagnosis of clinically actionable events compared to transtelephonic monitoring in 980 randomized patients, with results pending.
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