Key result
Diastolic dysfunction affects ~34% of nondiabetic metabolic syndrome patients, linked to hypertension and dyslipidemia.
Why the study?
The prevalence of diastolic dysfunction in non diabetic patients with metabolic syndrome and its association with metabolic syndrome components was unclear.
Cross-Sectional (n=100)
No
Answers are grounded in this paper and cite their sources.
Does not support practice changes; leaves open whether hypertension and dyslipidemia drive diastolic dysfunction in metabolic syndrome.
Background :The purpose of the present study was to study the prevalence of metabolic syndrome in non diabetic patients of metabolic syndrome Materials and Methods: 100 patients of non diabetic metabolic syndrome were screened using 2-D Echocardiogram.Results: 34% of non diabetic patients of metabolic syndrome had diastolic dysfunction, with no association found between the components of metabolic syndrome and diastolic dysfunction. There was a strong correlation between a past history of hypertension and dyslipidemia with diastolic dysfunction.Conclusion: Our findings suggest that long standing metabolic syndrome is a risk factor for diastolic dysfunction, rather than short term elevation of the metabolic syndrome parameters. Also it is likely that Diabetes and Prediabetes itself is responsible for most of the diastolic dysfunction that is seen in metabolic syndrome
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Kirty et al. (2021) conducted a cross-sectional in Metabolic syndrome without diabetes (n=100). Metabolic syndrome without diabetes was evaluated on Prevalence of diastolic dysfunction. In non-diabetic patients with metabolic syndrome, the prevalence of diastolic dysfunction was 34%, which significantly correlated with a past history of hypertension and dyslipidemia.
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