January 1, 2006Hypertension ResearchOpen Access

Left Ventricular Diastolic Dysfunction as Assessed by Echocardiography in Metabolic Syndrome

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Population

135 consecutive patients in their sixties diagnosed with atherosclerosis-related diseases but no history of…

Design

Cross-sectional

Authors

HMHisashi MasugataKagawa University SSShoichi SendaTokushima Bunri University FGFuminori GodaKagawa University Hospital

Discussion

Member takes

Implication

Metabolic syndrome may link to subclinical diastolic dysfunction; hypothesis-generating and requires prospective validation before practice change.

Structured PICO

Population

135 consecutive patients in their sixties diagnosed with atherosclerosis-related diseases (hypertension, diabetes mellitus, dyslipidemia) but no history of atherosclerotic cardiovascular diseases or stroke. Divided into metabolic syndrome (n=65, age 65+/-2.7) and non-metabolic syndrome (n=70, age 66+/-2.5) groups.

Comparator

Non-metabolic syndrome patients

Outcome

Left ventricular diastolic function assessed by the ratio of peak velocity of early rapid filling to peak velocity of atrial filling (E/A) and the Tei indexsurrogate

Patients with metabolic syndrome exhibit preclinical left ventricular diastolic dysfunction even in the absence of left ventricular hypertrophy or systolic dysfunction.

Limitations

Patients with severe LV systolic dysfunction show pseudonormalization of LV diastolic inflow patterns (though excluded in this study)
Mild hypertension seen in some patients with metabolic syndrome may have been responsible for the observed diastolic dysfunction

Cite This Study

Masugata et al. (2006) studied this question.

synapsesocial.com/papers/6a760ca0fa1990f79e613b3f https://doi.org/10.1291/hypres.29.897

Topics

Echocardiography

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Implication

Metabolic syndrome may link to subclinical diastolic dysfunction; hypothesis-generating and requires prospective validation before practice change.

Left Ventricular Diastolic Dysfunction as Assessed by Echocardiography in Metabolic Syndrome

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Topics

Left Ventricular Diastolic Dysfunction as Assessed by Echocardiography in Metabolic Syndrome

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

Topics

Also Consider