Metabolic syndrome is associated with abnormal left ventricular diastolic function independent of left ventricular mass
Why the study?
Does metabolic syndrome predict abnormal left ventricular structure and function in adults with normal LV function?
Population
607 adults with normal LV function
Comparison
Metabolic syndrome (≥3 criteria) vs Pre-Metabolic Syndrome and Absent
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
Metabolic syndrome may mark subclinical LV changes in preserved function; cross-sectional data leave causal prediction and practice implications open.
Structured PICO
Does metabolic syndrome predict abnormal left ventricular structure and function in adults with normal LV function?
P
Population
607 adults with normal LV function
I
Intervention
Metabolic syndrome (≥3 criteria)
C
Comparator
Pre-Metabolic Syndrome (1-2 criteria) and Absent (0 criteria)
O
Outcome
Left ventricular structure (LV mass) and systolic/diastolic function assessed by echocardiographysurrogate
Metabolic syndrome is associated with progressive worsening of left ventricular diastolic function independent of left ventricular mass.
Cite This Study
Fuentes et al. (2006) studied this question.