Key result
Chronic anemia drives compensatory cardiovascular adaptations that can progress to cardiac hypertrophy and heart disease.
Why the study?
The cardiovascular system's compensatory mechanisms and effects in anemic patients are complex and require synthesis from accumulated data.
Population
Anemic patients including those with chronic parasitic anemias
Design
Review of accumulated cardiovascular data in anemia
Authors
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May inform compensatory hemodynamics in anemia; leaves open relevance to modern outcomes or interventions.
Porter et al. (1953) conducted a review in Anemia. Anemia was evaluated. Chronic anemia induces cardiovascular adaptations including tachycardia, increased cardiac output, and selective blood shunting, and can ultimately lead to cardiac hypertrophy and organic heart disease.
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