Key result
Urografin 60% linked to marked transient ECG changes vs Ringer solution during coronary angiography.
Why the study?
The ECG changes induced by selective coronary angiography contrast injection and their underlying mechanisms were not fully characterized.
Population
95 consecutive patients undergoing selective coronary angiography
Comparison
Injection of 7 ml Urografin 60% contrast medium vs injection of Ringer solution
Design
Observational study recording ECG changes during coronary angiography
Authors
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Urografin may induce transient ECG changes during angiography; leaves open relevance to modern agents and clinical outcomes.
Observational (n=95)
Grendahl et al. (1972) conducted an observational in Patients undergoing selective coronary angiography (n=95). Injection of Urografin 60% vs. Ringer solution was evaluated on ECG changes. Injection of Urografin 60% during coronary angiography caused marked transient ECG changes, including increased QRS and QT duration and axis shifts, which were not seen with Ringer solution.
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