Why the study?
Does intracoronary contrast injection alter coronary blood flow in the immediate post-injection period in an open-chest dog model?
Population
16 open-chest dogs instrumented with electromagnetic flow probes on the left anterior descending artery
Comparison
ECG-gated intracoronary injection of contrast… vs Preinjection levels of coronary blood flow
Design
Preclinical
Follow-up
6 seconds post-injection
Authors
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May require timing adjustments in angiographic flow quantification; leaves human translation open.
Does intracoronary contrast injection alter coronary blood flow in the immediate post-injection period in an open-chest dog model?
Intracoronary contrast injection causes a transient but significant decrease in coronary blood flow within the first few seconds, which must be accounted for in angiographic flow measurements.
Hodgson et al. (1985) studied this question.
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