Key result
Chlorothiazide monotherapy lowers blood pressure in moderately severe to severe hypertension.
Why the study?
The effectiveness of chlorothiazide alone compared with standard antihypertensive therapy in patients with moderately severe and severe hypertension was evaluated.
Key points are not available for this paper at this time.
Population
11 patients with severe hypertension and 30 patients with moderately severe hypertension
Comparison
Chlorothiazide alone vs standard antihypertensive therapy vs combined chlorothiazide and standard therapy
Design
Comparative treatment evaluation study
Follow-up
6 months
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May aid BP control as adjunct in severe hypertension; leaves open efficacy pending randomized trials.
Finnerty et al. (1959) studied this question. Chlorothiazide alone was evaluated for its effectiveness compared to standard and combined antihypertensive therapies in 41 patients with moderately severe to severe hypertension.
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