Key result
Amiodarone therapy can cause rare leukocytoclastic vasculitis alongside typical cutaneous side effects.
Why the study?
Amiodarone is widely used for intractable cardiac arrhythmias despite well recognized cutaneous side-effects including rare leucocytoclastic vasculitis.
Case Report (n=1)
Rare amiodarone vasculitis warrants clinical vigilance; extends sparse case reports but leaves causality open.
Amiodarone is a valuable agent, used in the management of intractable cardiac arrhythmias. Its widespread use persists despite a list of well recognized side-effects. Skin reactions are common, usually presenting as photosensitivity or less frequently as a blue/grey pigmentation on light-exposed sites. Leucocytoclastic vasculitis following treatment with amiodarone has been reported rarely. We describe a further case and briefly review the unwanted cutaneous manifestations of amiodarone therapy.
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Dootson et al. (1994) conducted a case report in Amiodarone-induced vasculitis (n=1). Amiodarone was evaluated on Cutaneous side-effects including leucocytoclastic vasculitis. Amiodarone therapy can rarely cause leucocytoclastic vasculitis, in addition to more common cutaneous side-effects like photosensitivity and blue/grey pigmentation.
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