Key result
Aging is linked to ~34% higher capillary pressure, with no additional effect from hypertension.
Why the study?
Alterations of structure and function of the microcirculation in hypertension in the elderly and changes with normotensive aging have not been fully clarified.
Population
46 subjects in 3 groups: elderly hypertensives, elderly normotensives, young normotensives
Comparison
Elderly hypertensive vs elderly normotensive vs young normotensive subjects
Design
Cross-sectional study
Authors
Loading...
Hypertension may not further raise capillary pressure beyond aging; hypothesis-generating Level 5 data leave open any therapeutic implications.
Cross-Sectional (n=46)
Absolute Event Rate: 18.6% vs 13.9%
p-value: p=<0.05
James et al. (2006) conducted a cross-sectional in Hypertension (n=46). Aging and hypertension vs. Young normotensives was evaluated on Capillary pressure (p=<0.05). Aging significantly increased capillary pressure (17.6-18.6 mm Hg in elderly vs 13.9 mm Hg in young normotensives, P<0.05), with no additional effect from hypertension.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: