Key result
Primary systemic amyloidosis linked to intramural coronary occlusion causing angina, MI, and thromboembolic events.
Case Report (n=1)
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Highlights severe embolic and ischemic risks in primary cardiac amyloidosis without atherosclerosis; leaves open whether.
A patient had primary systemic amyloidosis with severe cardiac involvement and IgG paraproteinemia. Numerous intramural coronary arteries were occluded by amyloid deposits, but arteriosclerosis of the extramural arteries was absent. The amyloid coronary artery disease was associated with angina pectoris, a myocardial infarct, and mural thrombi which resulted in cerebral, renal, pulmonic, and coronary arterial emboli.
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R. F. Barth (1970) conducted a case report in Primary systemic amyloidosis with severe cardiac involvement and IgG paraproteinemia (n=1). Amyloid coronary artery disease was evaluated. Primary systemic amyloidosis was associated with amyloid occlusion of intramural coronary arteries leading to angina pectoris, myocardial infarction, and multiple thromboembolic events.
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