Correlation Between Fasting Blood Glucose and The Triglyceride-To-HDL Ratio in Patients with Uncontrolled Type 2 Diabetes Mellitus

Background: Type 2 diabetes mellitus has become a global health issue requiring serious attention, including in Indonesia. It is estimated that more than 830 million people worldwide live with diabetes. Type 2 diabetes mellitus is characterized by elevated blood glucose levels during fasting and after meals (postprandial hyperglycemia), which plays a significant role in the development of various complications and diseases. In the dyslipidemia associated with diabetes, the main characteristics include high triglyceride levels and low high-density lipoprotein cholesterol (HDL-C) levels. Objective: To determine the relationship between fasting blood glucose levels and the TG/HDL ratio in patients with uncontrolled type 2 diabetes mellitus at Dr. Bratanata Hospital in Jambi. Method: This study is descriptive-analytical in nature, using a cross-sectional approach with the participation of 40 Type 2 DM patients selected through purposive sampling. Fasting blood glucose was measured using the enzymatic (GOD-PAP) method at the Dr. Bratanata Hospital Laboratory in Jambi City, while triglycerides and HDL were measured using enzymatic methods. Analysis was performed using non-parametric statistical tests with data analyzed via Spearman’s correlation test. Results: The study found a mean fasting blood glucose level of 285.10 mg/dL and a mean triglyceride-to-HDL ratio of 4.26 mg/dL. Spearman’s correlation test yielded a P-value of 0.964 and a correlation coefficient of r = -0.007. Conclusion: There is no significant association between fasting blood glucose and the TG/HDL ratio in patients with uncontrolled type 2 diabetes mellitus. Further research is recommended to include variables such as dietary patterns, physical activity, BMI, and therapy to provide more comprehensive results to support improved monitoring of glucose and lipid profiles, particularly the TG/HDL ratio.