Key result
Obesity is linked to ~32.8-fold higher odds of significant tricuspid regurgitation after pacemaker implantation.
Why the study?
The prevalence and predictors of tricuspid regurgitation after dual-chamber permanent pacemaker implantation were not well defined.
Cohort (n=153)
Odds Ratio: 32.84 (95% CI 1.26–853.82)
p-value: p=0.04
Significant TR may occur post dual-chamber PPM; leaves open predictors, lead strategies, and need for prospective trials.
Objective To determine the prevalence of tricuspid regurgitation in patients with dual-chamber permanent pacemaker implantation. Methods This study included 153 patients undergoing permanent pacemaker implantation. All eligible candidates had baseline transthoracic echocardiography to rule out preexisting tricuspid regurgitation. Echocardiography across the tricuspid valve was repeated one month after permanent pacemaker implantation, and the frequency of significant tricuspid regurgitation was determined. The associations of potential effect modifiers (age, sex, height, body mass index categories, diabetes, and hypertension) with tricuspid regurgitation were assessed individually using simple and multivariable logistic regression models. Results After dual-chamber permanent pacemaker implantation, significant tricuspid regurgitation was present in 22 (15.8%) patients. Tricuspid regurgitation was significantly associated with body mass index >30 kg·m −2 (odds ratio = 32.84, 95% confidence interval: 1.26–853.82, p = 0.04). Conclusion Significant tricuspid regurgitation was present in substantial number of patients after dual-chamber pacemaker implantation and was independently associated with body mass index >30 kg·m −2 .
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Niazi et al. (2020) conducted a cohort in Tricuspid regurgitation (n=153). Dual-chamber permanent pacemaker implantation was evaluated on Significant tricuspid regurgitation at one month (OR 32.84, 95% CI 1.26-853.82, p=0.04). Dual-chamber permanent pacemaker implantation led to new significant tricuspid regurgitation in 15.8% of patients at 1 month, a risk strongly associated with BMI >30 kg/m2 (OR 32.84; p=0.04).
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