Key result
Tricuspid annuloplasty shows no significant difference in postoperative RVEF compared to replacement.
Why the study?
There is concern that clinical outcomes of tricuspid valve replacement are inferior to tricuspid annuloplasty in patients with severe functional tricuspid regurgitation, but comparative data on right ventricular volume and function changes are lacking.
Observational (n=40)
No
Mean Difference: -6.967 (95% CI -14.529–0.595)
Absolute Event Rate: 46.9% vs 42.4%
p-value: p=0.070
May favor TAP over TVR for postoperative RV preservation; hypothesis-generating and requires randomized confirmation.
BACKGROUND: There is a concern that clinical outcome of tricuspid valve replacement (TVR) is inferior compared with tricuspid annuloplasty (TAP). The aim of this study was therefore to compare changes in right ventricular (RV) volume and function following TAP with that following TVR on cardiac magnetic resonance imaging (CMR) in patients with severe functional tricuspid regurgitation (TR). METHODS AND RESULTS: Forty patients who underwent surgery for severe functional TR and who underwent CMR preoperatively and on postoperative follow-up (24.8±13.3 months after surgery) were enrolled. Thirteen patients underwent TAP (TAP group) and 27 patients underwent TVR (TVR group). Both RV end-diastolic and end-systolic volume indices decreased significantly after surgery (from 178.9±53.9 to 116.3±26.7 ml/m(2), P<0.001, and from 95.7±36.1 to 67.3±28.0 ml/m(2), P<0.001, respectively), without intergroup differences. In the TAP group, RV ejection fraction (EF) was preserved following surgery (from 43.3±9.5 to 46.9±10.9%, P=0.312). In the TVR group, however, it decreased significantly following surgery (from 51.8±9.2 to 42.4±12.3%, P<0.001). In addition, postoperative RVEF was lower in the TVR than TAP group, with a marginal significance (mean difference, -6.967; 95% confidence interval: -14.529 to 0.595; P=0.070). CONCLUSIONS: For patients with severe functional TR, both TAP and TVR are beneficial for reduction of RV volume indices. TAP, however, might be superior to TVR, because RVEF is well preserved following surgery. (Circ J 2016; 80: 1142-1147).
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Choi et al. (2016) conducted an observational in Severe functional tricuspid regurgitation (n=40). Tricuspid annuloplasty (TAP) vs. Tricuspid valve replacement (TVR) was evaluated on Postoperative Right Ventricular Ejection Fraction (RVEF) (mean difference -6.967, 95% CI -14.529 to 0.595, p=0.070). Tricuspid annuloplasty preserved right ventricular ejection fraction postoperatively compared to tricuspid valve replacement, which was associated with a significant decrease (mean difference -6.967% for TVR vs TAP, p=0.070).
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